DEFEROXAMINE (DFO) REDUCES CEREBRAL REPERFUSION INJURY AFTER BIRTH ASPHYXIA.• 2267
نویسندگان
چکیده
منابع مشابه
Birth asphyxia and cerebral palsy
resection,2 and in Britain we may well be dealing mostly with patients whose disease has infiltrated into surrounding tissue. The early disease in Japan may be different from that in Britain because the survival in Japanese patients (95%) is so much better than that in British patients (70%) that it cannot be explained purely on the basis of removing more affected nodes-and even RI resection in...
متن کاملMild hypothermia reduces expression of Fas/FasL and MMP-3 after cerebral ischemia-reperfusion in rats
Objective(s):To investigate the effects of local mild hypothermia on the expression of Fas, FasL and MMP-3 after cerebral ischemia-reperfusion in rats. Materials and Methods:Male Wistar rats were divided into sham-operated group (Sham), normothermia group (NT), and hypothermia group (HT). MCAO/R model was established by Longa’s method, and reperfusion was allowed after 2 hr occlusion. Mild hypo...
متن کاملHydroxyethyl starch reduces leukocyte adherence and vascular injury in the newborn pig cerebral circulation after asphyxia.
BACKGROUND AND PURPOSE Hydroxyethyl starch (HES) has beneficial effects on ischemic brain injury; however, its mechanism of action remains unclear. The present study was undertaken to test the hypothesis that HES can attenuate increases in leukocyte adherence and vascular permeability in the cerebral vasculature after global cerebral ischemia induced by asphyxia. METHODS Pial venular leukocyt...
متن کاملTreatment with Enriched Environment Reduces Neuronal Apoptosis in the Periinfarct Cortex after Cerebral Ischemia/Reperfusion Injury.
BACKGROUND/AIMS Enriched environment (EE) has been reported to exert neuroprotective effect in animal models of ischemic stroke. However, the underlying mechanism remains unclear. The purpose of this study was to investigate the effect of EE treatment on neuronal apoptosis in the periinfarct cortex after cerebral ischemia/reperfusion (I/R) injury. METHODS The cerebral I/R injury was establish...
متن کاملQuality of survival after severe birth asphyxia.
Thirty-one children who survived severe birth asphyxia defined by a 1-minute Apgar score of 0, or a 5-minute Apgar score of less than 4, have been seen at age 5 to 10 years for neurological and psychological assessment. Their progress has been compared with that of controls matched for sex, birthweight, gestational age, and social class. 29(93%) of the 31 asphyxiated group and all the controls ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1996
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199604001-02292